Maps are usually oriented so that North is up. That means the southwest corner is below and to the left of the intersecting lines. Since numbered streets are usually parallel, we're to assume that W 22nd street is parallel to W 20th street. That makes Broadway a transversal of parallel lines, and it makes the angle of interest a corresponding angle to the one whose measure is shown.
In this (assumed) geometry, corresponding angles are congruent, so the angle of interest has measure 105°.
y + 3 = - 4(x - 2) ← distribute the parenthesis
y + 3 = - 4x + 8 ( subtract 3 from both sides )
y = - 4x + 5 → d